Activity-based Chemical Proteomics

This book focuses on applications of functional proteomics methods to report on the activity of biomolecules with the use of chemical tools if applicable.  This includes the use of mechanism-based probes specific for enzyme classes (e.g. proteases), but also the measurement of protein interaction kinetics with ligands and small compounds, and monitoring enzyme-substrate kinetics and posttranslational modifications (phosphorylation, methylation, acetylation, ubiquitylation).