Robert O. Williams, III

This title demonstrates how advanced formulation designs and delivery technologies can be used to improve drug efficacy and treatment outcomes in particular therapeutic categories or disease states. It discusses nanoparticle systems for cancer treatments, and also presents cutting edge immono-regulation agents for transplantation and the local targeting of drugs, especially poorly water soluble drugs to provide enhanced therapeutic outcomes. In addition, this title highlights areas of therapy showing the most promise for improvement in clinical outcomes via advanced formulation design.

With contributions from international opinion leaders, this title addresses numerous advanced formulation and delivery technologies, including mucoadhesion, chronopharmaceutical delivery through smart delivery devices, targeted nanoparticle systems, and advanced solubilization technologies with liposomal delivery…covers major therapeutic categories such as infectious disease, cancer, CNS disorders, and endocrine disorders…includes pre-clinical or clinical evidence showing an enhanced therapy achieved with advanced formulation design…discusses difficult-to-treat tumors requiring chemotherapeutic agents to pass the blood brain barrier, which is of particular interest for improving the overall efficacy of such drugs with severe side-effects when administered in high doses